Concomitant infections of Plasmodium falciparum and Wuchereria bancrofti on the Kenyan coast
2006

Infections of Malaria and Filariasis on the Kenyan Coast

Sample size: 208 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ephantus J. Muturi, Charles M. Mbogo, Joseph M. Mwangangi, Zipporah W. Ng'ang'a, Ephantus W. Kabiru, Charles Mwandawiro, John C. Beier

Primary Institution: Kenya Medical Research Institute

Hypothesis

What is the prevalence of concomitant infections of Plasmodium falciparum and Wuchereria bancrofti in mosquito and human populations along the Kenyan Coast?

Conclusion

The study suggests that integrated control efforts for malaria and bancroftian filariasis are necessary in areas where both diseases co-exist.

Supporting Evidence

  • 1.1% of An. gambiae s.l collected in Jilore had concomitant infections.
  • 4.3% of individuals in Jilore were found to have both parasites.
  • Wuchereria-infected mosquitoes had higher sporozoite rates compared to non-infected mosquitoes.

Takeaway

This study looked at how two diseases, malaria and filariasis, can happen together in people and mosquitoes. It found that while some mosquitoes can carry both, it doesn't help them spread the diseases more.

Methodology

Mosquitoes were collected using pyrethrum spray sheet collection, and blood samples were taken from individuals using a finger prick technique.

Limitations

The study was limited by the small sample size and the inability to replicate each set of villages.

Participant Demographics

Participants were individuals aged four years and above from Jilore and Shakahola villages.

Statistical Information

P-Value

p = 0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1475-2883-5-8

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