Identifying Factor XI Deficiency in Holstein Cattle in Turkey
Author Information
Author(s): Meydan Hasan, Yildiz Mehmet A, Özdil Fulya, Gedik Yasemin, Özbeyaz Ceyhan
Primary Institution: Ankara University, Faculty of Agriculture, Animal Sciences
Hypothesis
What is the frequency of the mutant FXI allele in Holstein cattle reared in Turkey?
Conclusion
This study found that only four out of 225 Holstein cows tested in Turkey carried the FXI deficiency.
Supporting Evidence
- Only four out of 225 Holstein cows tested carried the FXI deficiency.
- The frequency of the mutant FXI allele was found to be 0.9%.
- The prevalence of heterozygous cows was found to be 1.8%.
- This is the first report of FXI deficiency in Holstein cattle in Turkey.
Takeaway
The study looked at 225 cows to see if they had a genetic problem that makes them bleed too much, and found that only a few had it.
Methodology
DNA was extracted from blood samples, and FXI genotypes were identified using PCR and DNA sequencing.
Limitations
The frequency of the mutant FXI allele needs to be confirmed by further analyses on cattle in Turkey.
Participant Demographics
Holstein cows reared in Turkey.
Digital Object Identifier (DOI)
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