Whole Genome Analysis of a Wine Yeast Strain
Author Information
Author(s): Nicole C. Hauser, Kurt Fellenberg, Rosario Gil, Sonja Bastuck, Jörg D. Hoheisel, Jose E. Pérez-Ortín
Primary Institution: Deutsches Krebsforschungszentrum
Hypothesis
What are the genetic differences between wine yeast strains and laboratory strains?
Conclusion
The study found significant differences in gene expression patterns between the wine yeast strain T73 and the laboratory strain S288c.
Supporting Evidence
- More than 40 genes showed significant differences in expression patterns between the two yeast strains.
- The wine yeast strain T73 is less colonized by Ty transposons compared to the laboratory strain S288c.
- Specific genes related to sulphite resistance and oxygen response were analyzed in detail.
Takeaway
Scientists looked at the genes of a special type of yeast used for making wine and found that it behaves differently than regular lab yeast.
Methodology
DNA-array analyses were performed on the wine yeast strain T73 and the standard laboratory strain S288c to compare gene expression.
Limitations
The study compared strains with different growth rates and genetic backgrounds, which may affect gene expression.
Digital Object Identifier (DOI)
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