MiCK: A Database of Gut Microbial Genes Linked with Chemoresistance in Cancer Patients
Author Information
Author(s): Shahzaib Muhammad, Muaz Muhammad, Zubair Muhammad Hasnain, Kayani Masood Ur Rehman
Primary Institution: National University of Sciences and Technology (NUST), Islamabad, Pakistan
Hypothesis
The study aims to develop a comprehensive database that catalogs microbial gene sequences associated with chemoresistance in cancer patients.
Conclusion
The Microbial Chemoresistance Knowledgebase (MiCK) provides a valuable resource for understanding and mitigating chemoresistance in cancer treatment.
Supporting Evidence
- MiCK contains 1.6 million sequences of 29 gene types linked to chemoresistance and drug metabolism.
- The database architecture supports efficient data search, retrieval, and download functionalities.
- MiCK aims to facilitate the understanding and mitigation of chemoresistance in cancers.
Takeaway
Scientists created a big database that helps understand how gut bacteria can make cancer treatments less effective.
Methodology
The database was created by manually curating microbial gene sequences from literature and existing databases, focusing on their association with chemoresistance.
Digital Object Identifier (DOI)
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