Seasonal Variations in Triptan Prescription in Japan
Author Information
Author(s): Tatsumoto Muneto, Hirata Koichi, Nakayama Takeo, Yamato Kentaro, Sano Hiromi, Inuyama Lyo
Primary Institution: Otsuka Pharmaceutical Co. Ltd, Tokyo, Japan
Hypothesis
Variations in seasonality in Japan are associated with the onset of migraine.
Conclusion
The study results suggest that seasons can impact the onset of migraine, and clinicians may advise preventive actions from winter to reduce migraine onsets in spring.
Supporting Evidence
- 12,986 patients were analyzed in 2019.
- The mean number of triptan prescriptions was lower in winter compared to spring.
- 74.1% of the sample were female.
- The average age of participants was 44.1 years.
- Patients were categorized into four seasonal groups for analysis.
Takeaway
This study found that the time of year can affect how often people get migraines, and doctors should help patients prepare for migraine season.
Methodology
The study analyzed medical claims data and meteorological data to assess seasonal differences in triptan prescriptions among migraine patients.
Potential Biases
Potential unmeasured confounders related to migraines may exist.
Limitations
The study may not accurately reflect individual weather conditions experienced by patients and does not include over-the-counter medications.
Participant Demographics
74.1% female, mean age 44.1 years.
Statistical Information
P-Value
<0.001
Confidence Interval
−0.169 to −0.065
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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