Thermogenic effect of an acute ingestion of a weight loss supplement
2009

Effects of a Weight Loss Supplement on Energy Expenditure

Sample size: 10 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hoffman Jay R, Kang Jie, Ratamess Nicholas A, Rashti Stefanie L, Tranchina Christopher P, Faigenbaum Avery D

Primary Institution: The College of New Jersey

Hypothesis

Does acute ingestion of a weight loss supplement affect resting oxygen uptake, caloric expenditure, heart rate, and blood pressure in healthy individuals?

Conclusion

The study found that a weight loss supplement significantly increases energy expenditure and elevates heart rate and blood pressure in young, healthy individuals.

Supporting Evidence

  • Subjects showed a 28.9% increase in VO2 after taking the supplement compared to placebo.
  • Energy expenditure was significantly higher in the supplement group at 1.28 kcal/min compared to 1.00 kcal/min in the placebo group.
  • Heart rate was significantly elevated during the second and third hours after taking the supplement.
  • Systolic blood pressure was significantly higher in the supplement group compared to placebo.

Takeaway

Taking a weight loss supplement can help your body burn more energy and make your heart beat faster.

Methodology

Ten subjects participated in a double-blind, crossover study where they ingested either a weight loss supplement or a placebo, and various metabolic measures were taken over three hours.

Potential Biases

Potential bias due to funding from a company that produces the supplement.

Limitations

The study had a small sample size and short duration, and results may not be generalizable to all populations.

Participant Demographics

5 male and 5 female subjects, average age 20.2 years, healthy and physically active.

Statistical Information

P-Value

0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1550-2783-6-1

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