Characteristics influencing acute laryngitis and laryngeal obstruction in children: A retrospective study
2024

Factors Affecting Laryngitis and Breathing Problems in Kids

Sample size: 390 publication Evidence: moderate

Author Information

Author(s): Yueting Zhu, Xuyuan Sun, Guangping Liu

Primary Institution: Tianjin Children’s Hospital (Children’s Hospital of Tianjin University), Tianjin, China

Hypothesis

What clinical characteristics influence laryngeal obstruction in children with acute laryngitis?

Conclusion

The study found that higher degrees of laryngeal obstruction in children are associated with more severe symptoms and elevated levels of certain inflammatory markers.

Supporting Evidence

  • The study included 390 children treated for acute laryngitis over three years.
  • Children with higher degrees of laryngeal obstruction showed significantly more severe symptoms.
  • Inflammatory markers like TNF-α and IL-6 were higher in children with severe laryngeal obstruction.

Takeaway

This study looked at kids with throat infections and found that those with more serious breathing problems showed worse symptoms and higher levels of certain chemicals in their blood.

Methodology

A retrospective study analyzing clinical data from 390 children treated for acute laryngitis from February 2021 to February 2024.

Limitations

The study was conducted at a single center and did not analyze different medication plans.

Participant Demographics

52% boys and 48% girls, with a history of allergies in 11.3% of participants.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1097/MD.0000000000040885

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