A Case of Pill-Induced Esophagitis with Mucosal Dissection
1998
Case of Pill-Induced Esophagitis with Mucosal Dissection
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Wataru Adachi, Hiroyuki Watanabe, Kazuyuki Yazawa, Naohiko Koide, Shoichiro Koike, Jun Amano, Chisato Tamai
Primary Institution: Shinshu University School of Medicine
Hypothesis
Is there a link between pill-induced esophagitis and mucosal dissection?
Conclusion
The case demonstrates that cefotiam hydrochloride can cause esophagitis and mucosal dissection.
Supporting Evidence
- The patient experienced severe odynophagia and retrosternal pain after taking the medication.
- Endoscopy revealed detached mucosa and acute esophagitis.
- Histological examination confirmed the esophageal mucosa was detached from the lamina propria.
- After treatment, the esophagus returned to almost normal without scarring.
Takeaway
A patient had a sore throat after taking a large pill, which caused damage to his esophagus, but he got better after treatment.
Methodology
The case was diagnosed through endoscopy and histological examination.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
66-year-old male with combined valvular heart disease.
Want to read the original?
Access the complete publication on the publisher's website