Thottapalayam Virus: A New Hantavirus from Shrews
Author Information
Author(s): Song Jin-Won, Baek Luck Ju, Schmaljohn Connie S., Yanagihara Richard
Primary Institution: Korea University College of Medicine
Hypothesis
Whether Thottapalayam virus (TPMV) is naturally harbored by an insectivore host or represents spillover from a rodent reservoir host is unknown.
Conclusion
Thottapalayam virus is distinct from rodent-borne hantaviruses and may have a broader host range.
Supporting Evidence
- 12 out of 363 serum samples were reactive to TPMV.
- TPMV shows no cross-neutralization with any other hantavirus.
- TPMV appears to be genetically divergent from other hantaviruses.
Takeaway
Scientists studied a virus called Thottapalayam that comes from shrews, and they found it might be different from other viruses that come from rats.
Methodology
The study involved serologic testing of serum specimens from residents of Mumbai for evidence of TPMV and SEOV infection.
Limitations
The specificity of immunoreactivity to TPMV could not be verified by PRNT.
Participant Demographics
Residents of Mumbai, India.
Statistical Information
P-Value
0.033
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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