Traffic-related air pollution and respiratory symptoms among asthmatic children, resident in Mexico City: the EVA cohort study
2008

Traffic Pollution and Asthma in Children

Sample size: 197 publication 10 minutes Evidence: high

Author Information

Author(s): Maria-Consuelo Escamilla-Nuñez, Albino Barraza-Villarreal, Leticia Hernandez-Cadena, Hortensia Moreno-Macias, Matiana Ramirez-Aguilar, Juan-Jose Sienra-Monge, Marlene Cortez-Lugo, Jose-Luis Texcalac, Blanca del Rio-Navarro, Isabelle Romieu

Primary Institution: Instituto Nacional de Salud Pública, Mexico

Hypothesis

Does traffic-related air pollution increase respiratory symptoms in asthmatic children in Mexico City?

Conclusion

Respiratory symptoms in asthmatic children were significantly associated with exposure to traffic exhaust, especially from natural gas and diesel-fueled vehicles.

Supporting Evidence

  • Wheezing increased by 8.8% with a 17.4 μg/m3 increase in PM2.5.
  • An increase of 34 ppb in NO2 was associated with a 9.1% increase in wheezing.
  • Traffic density was significantly related to respiratory symptoms in asthmatic children.

Takeaway

Kids with asthma living near busy roads have more coughing and wheezing because of the pollution from cars and trucks.

Methodology

A panel study followed 147 asthmatic and 50 healthy children for 22 weeks, assessing symptoms and exposure to pollutants using mixed-effect models.

Potential Biases

Selection bias due to voluntary participation and potential misclassification of exposure.

Limitations

The study's exposure assessment may have misclassified individual exposure levels, and participants were not representative of the general population.

Participant Demographics

Participants included 147 asthmatic children (61% male) and 50 healthy children aged 6 to 14 years.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 2.4% to 15.5%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1465-9921-9-74

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