Associations Between Functional Networks of Physical Reserve, Postural Instability, and White Matter Lesions
2024

Mapping Functional Networks of Physical Reserve and Postural Instability

Sample size: 22 publication

Author Information

Author(s): Hsu Chun-Liang, Holtzer Roee, Tam Roger, Alkeridy Walid, Liu-Ambrose Teresa

Primary Institution: The Hong Kong Polytechnic University

Hypothesis

This study aims to map functional networks associated with physical reserve and examine the relationship between physical reserve, white matter hyperintensities, and postural balance.

Conclusion

Higher physical reserve helps maintain postural balance despite the presence of white matter lesions.

Supporting Evidence

  • Physical reserve was defined as the unexplained variance in Timed-Up-and-Go test results.
  • Functional neural networks were identified using general linear models.
  • High physical reserve was associated with maintained postural balance despite white matter lesions.

Takeaway

Older adults with better physical reserve can stay balanced even if they have brain issues.

Methodology

The study used a cross-sectional design and analyzed the Timed-Up-and-Go test results along with brain imaging data.

Participant Demographics

Community-dwelling older adults with subcortical ischemic vascular cognitive impairment.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0149

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