Association between “Life's Essential 8” cardiovascular health and apparent treatment-resistant hypertension among US adults from the NHANES, 2005 to 2018
2024

Healthy Lifestyle and Treatment-Resistant Hypertension

Sample size: 7474 publication 10 minutes Evidence: high

Author Information

Author(s): Xu Zhong-jiao, Shen Ru-ming, Hu Wu-ming, Shen Jia-yi, Wu Xiao-yan, Lv Ling-chun

Primary Institution: The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Central Hospital, Zhejiang, China

Hypothesis

The study aimed to explore the association between a healthy lifestyle, as measured by the Life's Essential 8 score, and apparent treatment-resistant hypertension (aTRH) in the general population.

Conclusion

Higher Life's Essential 8 scores are significantly associated with a lower risk of apparent treatment-resistant hypertension.

Supporting Evidence

  • Participants with higher LE8 scores exhibited lower risks of aTRH.
  • Moderate and high CVH were associated with 47% and 76% lower risks of aTRH, respectively.
  • Physical activity, BMI, and blood glucose were significantly associated with aTRH.

Takeaway

Eating well, exercising, and taking care of your health can help lower the chances of having hard-to-treat high blood pressure.

Methodology

The study analyzed NHANES data from 2005 to 2018 using logistic regression models to explore the association between Life's Essential 8 scores and aTRH.

Potential Biases

Potential information bias due to reliance on self-reported questionnaires.

Limitations

The study relied on self-reported data for lifestyle factors, which may introduce bias, and it was cross-sectional, limiting causal inferences.

Participant Demographics

52.65% female, 48.11% non-Hispanic white, median age 64 years.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI, 0.14 to 0.38

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.3389/fcvm.2024.1453563

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