Measuring X-ray Attenuation in Digital Mammography
Author Information
Author(s): John J Heine, Jerry A Thomas
Primary Institution: Moffitt Cancer Center
Hypothesis
Can effective x-ray attenuation coefficients be accurately measured from full field digital mammography systems for breast density calibration?
Conclusion
The calibration quantities from FFDM systems can be used for data acquired on similar systems.
Supporting Evidence
- Breast density is a significant breast cancer risk factor.
- Calibration data collection can be reduced by applying a simple normalization technique.
- Intrasystem calibration variation was on the order of four percent.
Takeaway
This study looks at how to measure breast density using digital mammography, which helps in understanding breast cancer risk.
Methodology
Logarithmic response calibration curves and effective x-ray attenuation coefficients were measured from two FFDM systems using breast tissue equivalent phantoms.
Potential Biases
Potential bias due to variations in detector response and calibration methods.
Limitations
The study is limited to two similar systems and does not assess natural serial variation in regression parameters.
Statistical Information
P-Value
0.56
Confidence Interval
0.784–0.882
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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