Cervical Pillar Hyperplasia and Degenerative Joint Disease
Author Information
Author(s): Maja Stupar, Cynthia K. Peterson
Primary Institution: Canadian Memorial Chiropractic College
Hypothesis
There would be a clinically important association of C ≥ .4 (p ≤ .05) and/or OR ≥ 5.0 between the presence of cervical pillar hyperplasia (CPH) at specific cervical segments and the presence of degenerative joint disease (DJD) at specific cervical levels.
Conclusion
Cervical pillar hyperplasia (CPH) is weakly-to-moderately associated with the presence of degenerative joint disease (DJD), particularly at specific cervical levels.
Supporting Evidence
- CPH prevalence was 11%, 11%, 43%, and 50% at C3, C4, C5, and C6, respectively.
- DDD prevalence was highest at the C5–6 and C6–7 levels.
- The strongest associations were between C4 CPH and C4–5 DDD and between C5 CPH and C5–6 DDD.
- Age-stratified results showed some categories reaching OR ≥ 5.0.
- Overall, CPH may contribute to approximately 9–18% of the development of DJD.
Takeaway
This study looked at how a condition called cervical pillar hyperplasia might be linked to neck problems in adults. It found that while there is some connection, it's not very strong.
Methodology
The study analyzed 240 radiographs from subjects aged 40 to 69, assessing the presence of CPH and DJD at specific cervical levels using contingency coefficients and odds ratios.
Potential Biases
One assessor could not be blinded to the presence/absence of cervical pillar hyperplasia while assessing for DJD.
Limitations
Poor visualization of certain cervical levels and potential assessment bias due to one assessor being aware of CPH status.
Participant Demographics
Subjects aged 40 to 69 years, matched for age and gender.
Statistical Information
P-Value
p ≤ .05
Confidence Interval
95% CI > 1.0
Statistical Significance
p ≤ .05
Digital Object Identifier (DOI)
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