Mycobacterium phlei cell wall complex directly induces apoptosis in human bladder cancer cells
1999
Mycobacterium phlei cell wall complex and bladder cancer
publication
Evidence: moderate
Author Information
Author(s): Filion M C, Lépicier P, Morales A, Phillips N C
Primary Institution: Faculté de Pharmacie, Université de Montréal
Hypothesis
Does Mycobacterium phlei mycobacterial cell complex induce apoptosis in human bladder cancer cells?
Conclusion
Mycobacterium phlei cell wall complex induces apoptosis in bladder cancer cells and may stimulate anti-cancer activity through immune response.
Supporting Evidence
- Mycobacterium phlei cell wall complex induces apoptosis in bladder cancer cells.
- The complex stimulates the production of interleukin 12 in immune cells.
- MCC does not directly kill bladder cancer cells but affects their proliferation.
Takeaway
This study found that a part of a bacteria can help kill bladder cancer cells by making them die on their own.
Methodology
The study investigated the effects of Mycobacterium phlei cell wall complex on bladder cancer cells and its ability to induce apoptosis.
Digital Object Identifier (DOI)
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