Randomised trials relevant to mental health conducted in low and middle-income countries: a survey
2008

Mental Health Trials in Low and Middle-Income Countries

Sample size: 177 publication Evidence: low

Author Information

Author(s): Rebecca J Syed, Clive E Adams, Prathap Tharyan, Mahesh Jayaram, Lelia Duley

Hypothesis

What is the extent and quality of mental health trials conducted in low and middle-income countries?

Conclusion

Trial research activity from low and middle-income countries in mental health appears to be low and does not adequately reflect the health needs.

Supporting Evidence

  • Only 3% of the records searched were relevant to mental health.
  • 68% of trials had less than 100 participants.
  • 80% of studies evaluated pharmacological interventions.

Takeaway

This study looked at mental health trials in poorer countries and found that very few are being done, which means people there might not be getting the help they need.

Methodology

The study involved searching electronic records for randomised trials from low and middle-income countries published in 1991, 1995, and 2000, focusing on mental health.

Potential Biases

Potential bias due to the low reporting of methodological quality and funding sources.

Limitations

The study may not have identified all relevant trials due to time constraints and poor indexing in some databases.

Participant Demographics

Participants were primarily adults aged 18-60, with a mix of genders, and included those with unipolar depression and schizophrenia.

Statistical Information

P-Value

0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-244X-8-69

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