Clinical safety-in-use study of a new tampon design
2003

Safety Study of a New Tampon Design

Sample size: 110 publication Evidence: moderate

Author Information

Author(s): Stacey E. Shehin, Michaelle B. Jones, Anne E. Hochwalt, Frank C. Sarbaugh, Stephen Nunn

Primary Institution: Procter & Gamble Company

Hypothesis

The new experimental Tampax tampon and applicator are as safe as the currently marketed Tampax tampon and applicator.

Conclusion

The study found no significant differences in safety profiles between the new and currently marketed tampons.

Supporting Evidence

  • The study involved 110 women who completed the safety assessments.
  • There were no significant differences in the prevalence of selected microorganisms between the two tampon types.
  • Both tampons had similar low incidences of reported symptoms during use.
  • The experimental tampon received a more favorable overall product rating.

Takeaway

This study tested a new tampon to see if it was safe to use, and it turned out to be just as safe as the old one.

Methodology

A 2-month, single-blind, randomized, crossover study where each subject served as her own control, evaluating safety through gynecological and microbiological assessments.

Limitations

Some subjects were not evaluable for statistical analyses due to non-compliance with the protocol.

Participant Demographics

Healthy adult women aged 18-45, mostly Caucasian (94%).

Statistical Information

P-Value

0.003

Statistical Significance

p = 0.003

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