Ovarian Cancer Incidence Trends in Canada
Author Information
Author(s): Zhang J, Ugnat A-M, Clarke K, Mao Y
Primary Institution: Environmental Risk Assessment and Case Surveillance Division, Laboratory Centre for Disease Control, Health Canada
Hypothesis
This study examines the impact of age, period, and cohort effects on ovarian cancer incidence trends in Canada from 1969 to 1993.
Conclusion
The study found that the incidence rates of certain types of ovarian cancer increased significantly, while others decreased or remained unchanged.
Supporting Evidence
- Age-standardized incidence rates of serous, endometrioid, clear cell, and germ cell tumours increased significantly.
- Rates of sex cord-stromal and other classified epithelial ovarian tumours decreased considerably.
- The rates of mucinous and NOS/unclassified tumours remained unchanged.
- Cohort effects had a major impact on incidence trends of several ovarian cancer types.
Takeaway
The study looked at how different types of ovarian cancer changed over time in Canada, showing that some types became more common while others became less common.
Methodology
Age-period-cohort analysis was used to study the incidence trends.
Limitations
Further studies are needed to consider various etiologies and changes in classification criteria.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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