Detection of Aortic Calcification during Vertebral Fracture Assessment (VFA) Compared to Digital Radiography Aortic Calcification Detection
2007

Detecting Aortic Calcification Using Bone Densitometry Images

Sample size: 174 publication 10 minutes Evidence: moderate

Author Information

Author(s): John T. Schousboe, Kevin E. Wilson, Thomas N. Hangartner

Primary Institution: Park Nicollet Health Services

Hypothesis

A high percentage of VFA's would include the abdominal aorta if the technician was specifically instructed to include this region during VFA acquisition.

Conclusion

VFA imaging can detect radiographic AAC, an important cardiovascular disease risk factor, while assessing for vertebral fractures.

Supporting Evidence

  • 90% of the VFA images were evaluable for AAC.
  • The intraclass correlation coefficient between VFA and radiographic scores was 0.80.
  • VFA imaging exposes patients to significantly less radiation than standard radiographs.

Takeaway

Doctors can use special images taken for bone health to also check for heart problems in older women.

Methodology

The study involved 174 postmenopausal women who underwent bone densitometry and imaging to assess abdominal aortic calcification.

Potential Biases

Participants may have been healthier than the general population, potentially skewing results.

Limitations

The prevalence of AAC was lower than expected, and results are only applicable to post-menopausal women.

Participant Demographics

Postmenopausal women aged 55 and older, primarily white and black.

Statistical Information

P-Value

0.034

Confidence Interval

95% C.I. 0.68–0.87

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0000715

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