Antihypertensive and antioxidant effects of dietary black sesame meal in pre-hypertensive humans
2011

Effects of Black Sesame Meal on Blood Pressure and Oxidative Stress

Sample size: 30 publication 10 minutes Evidence: moderate

Author Information

Author(s): Wichitsranoi Jatuporn, Weerapreeyakul Natthida, Boonsiri Patcharee, Settasatian Chatri, Settasatian Nongnuch, Komanasin Nantarat, Sirijaichingkul Suchart, Teerajetgul Yaovalak, Rangkadilok Nuchanart, Leelayuwat Naruemon

Primary Institution: Faculty of Associated Medical Sciences, Khon Kaen University

Hypothesis

Black sesame meal may have an antihypertensive effect in pre-hypertensive humans via improving antioxidant status and decreasing oxidant stress.

Conclusion

The study suggests that dietary black sesame meal can reduce blood pressure and improve antioxidant status in pre-hypertensive individuals.

Supporting Evidence

  • Black sesame meal significantly decreased systolic blood pressure after 4 weeks.
  • Plasma malondialdehyde levels decreased significantly in the black sesame meal group.
  • Vitamin E levels increased significantly in the black sesame meal group.

Takeaway

Eating black sesame meal might help lower blood pressure and make your body better at fighting off bad stuff.

Methodology

A double-blind, placebo-controlled study where participants took black sesame meal or placebo for 4 weeks, measuring blood pressure and oxidative stress markers.

Limitations

The study did not measure endothelium-dependent vasorelaxation or other antioxidants like vitamin C.

Participant Demographics

30 middle-aged individuals (22 men and 8 women) with prehypertension.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1475-2891-10-82

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