A randomized controlled trial of sucrose and/or pacifier as analgesia for infants receiving venipuncture in a pediatric emergency department
2007

Using Sucrose and Pacifiers to Reduce Pain in Infants During Blood Tests

Sample size: 84 publication 10 minutes Evidence: moderate

Author Information

Author(s): Curtis Sarah J, Jou Hsing, Ali Samina, Vandermeer Ben, Klassen Terry

Primary Institution: Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada

Hypothesis

Does sucrose or pacifier use reduce pain during venipuncture in infants?

Conclusion

Pacifiers are effective in reducing crying time during venipuncture in infants aged 0–3 months, while sucrose alone requires further investigation.

Supporting Evidence

  • Pacifier use significantly reduced crying time during venipuncture.
  • Sucrose alone did not significantly reduce pain scores.
  • Younger infants showed greater pain relief with sucrose and pacifier.
  • The study included 84 infants who were randomized into four groups.

Takeaway

Using a pacifier can help babies feel less pain during blood tests, and it's easy to use. Sucrose might help too, but we need to study it more.

Methodology

This was a double and single blind, placebo-controlled randomized trial conducted in a pediatric emergency department with infants aged 0-6 months.

Potential Biases

Observer bias was present as the research nurse was not blinded to pacifier use.

Limitations

The study had a convenience sample and imbalances in baseline characteristics, particularly age.

Participant Demographics

Infants aged 0-6 months requiring venipuncture, with a median age of 48 days.

Statistical Information

P-Value

p < 0.0029

Confidence Interval

(1.58, 5.84)

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2431-7-27

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