Trends in mortality from Hodgkin's disease in western and eastern Europe
2002

Trends in Hodgkin's Disease Mortality in Europe

publication Evidence: moderate

Author Information

Author(s): Fabio Levi, Francesco Lucchini, Elio Negri, Paolo Boyle, Carlo La Vecchia

Primary Institution: Cancer Epidemiology Unit and Cancer Registries of Vaud and Neuchâtel, Switzerland

Hypothesis

How have mortality rates from Hodgkin's disease changed in western and eastern Europe over the decades?

Conclusion

Hodgkin's disease mortality rates have significantly declined in western Europe and the USA, but have stagnated in eastern European countries.

Supporting Evidence

  • Hodgkin's disease mortality rates declined by about 75% in western Europe and the USA from the late 1960s to the late 1990s.
  • Eastern European countries only saw a 40% decline in Hodgkin's disease mortality during the same period.
  • Mortality rates in Japan were significantly lower than in western countries, with continued declines observed.

Takeaway

Hodgkin's disease used to be very deadly, but now it's much less so in western countries, while eastern countries haven't seen the same improvements.

Methodology

The study analyzed mortality trends using WHO mortality database data, focusing on age-adjusted rates across various European countries and Japan.

Limitations

The study may not account for all factors influencing mortality trends, particularly in eastern European countries.

Participant Demographics

The study included data from various European countries and Japan, focusing on both men and women.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600452

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