First report of an HIV-1 triple recombinant in Buenos Aires, Argentina
Author Information
Author(s): Pando María A, Eyzaguirre Lindsay M, Segura Marcela, Bautista Christian T, Marone Rubén, Ceballos Ana, Montano Silvia M, Sánchez José L, Weissenbacher Mercedes, Ávila María M, Carr Jean K
Primary Institution: Centro Nacional de Referencia para el SIDA, Universidad de Buenos Aires
Hypothesis
What is the genetic diversity of HIV-1 strains among men who have sex with men in Buenos Aires?
Conclusion
This study identified a new triple recombinant strain of HIV-1 combining subtypes B, C, and F in Buenos Aires.
Supporting Evidence
- Six samples were subtype B, three were BF recombinants, and one was a triple recombinant of subtypes B, C, and F.
- The young man infected with the triple recombinant reported multiple sexual partners.
- This is the first report of a triple recombinant HIV-1 strain in the region.
Takeaway
Scientists found a new type of HIV that mixes three different versions of the virus in a young man from Buenos Aires.
Methodology
The study involved nearly full-length genetic sequencing of 10 HIV-1 samples from men who have sex with men in Buenos Aires.
Limitations
The study lacks additional patient information to determine the exact nature of the infections.
Participant Demographics
Participants were men who have sex with men in Buenos Aires, Argentina.
Digital Object Identifier (DOI)
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