Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum
2025

Erratum on Piezo1 Deletion in Macrophages and Liver Fibrosis

Sample size: 6 publication

Author Information

Author(s): Luo Shangfei, Zhao Xiaoduo, Jiang Jintao, Deng Bo, Liu Silin, Xu Honglin, Tan Qiaorui, Chen Yu'an, Zhang Ziyan, Pan Xianmei, Wan Rentao, Chen Xiaoting, Yao Youfen, Li Jing

Primary Institution: Lingnan Medical Research Center, Guangzhou University of Chinese Medicine

Conclusion

The erratum corrects an image overlap error in the original publication regarding the expression of Piezo1 in macrophages in liver fibrosis.

Supporting Evidence

  • The original paper contained an error in partially overlapping images.
  • The correct figure shows the expression of Piezo1 in macrophages in fibrotic livers.
  • Data are presented as mean ± S. E. M.
  • Human samples included various liver conditions.
  • Mice samples were used to study the effects of Piezo1 deletion.

Takeaway

The study found that a specific deletion in macrophages can help protect against liver fibrosis in mice, but there was a mistake in the images presented.

Limitations

The original paper contained an error in image representation.

Participant Demographics

Human samples included control (n = 3), HBV-related HCC (n = 4), PBC (n = 5), BA (n = 4), cholangiectasis (n = 4); mice samples (n = 6 for each group); cell samples (n = 4 for each group).

Statistical Information

P-Value

P < 0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7150/thno.107640

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