A tale of two time periods: ovarian cancer trends in Ontario
2007

Ovarian Cancer Trends in Ontario

Sample size: 3825 publication Evidence: moderate

Author Information

Author(s): Laurie Elit, Bondy S.J., Chen Z., Paszat L.

Primary Institution: McMaster University

Hypothesis

What are the trends in incidence and survival rates for epithelial ovarian cancer in Ontario over two time periods?

Conclusion

The age-standardized incidence and mortality rates for ovarian cancer in Ontario have remained stable, but advances in management have led to improved survival for women initially treated with surgery.

Supporting Evidence

  • The age-standardized incidence of ovarian cancer remained stable during 1996–2001.
  • A shift to a younger age at diagnosis was found between the two time periods.
  • Advances in management have led to an improvement in survival for women treated with surgery.

Takeaway

This study looked at how ovarian cancer rates and survival changed over time in Ontario. It found that while the number of cases stayed the same, women are living longer after treatment now than they did before.

Methodology

The study analyzed population-based trends in incidence and survival rates for epithelial ovarian cancer using data from hospital records and cancer registries.

Limitations

The study lacked detailed information on disease-related variables and treatment for the most recent cohort.

Participant Demographics

The study included women with epithelial ovarian cancer treated with abdominal surgery in Ontario from 1996 to 2001.

Statistical Information

P-Value

p<0.0001

Confidence Interval

95%ci lower: 0.83, 95%ci upper: 0.98

Statistical Significance

p<0.0001

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