Bone Quality in Patients with Raynaud Phenomenon
Author Information
Author(s): Lurati Alfredo M
Primary Institution: Fornaroli Hospital, Magenta, Italy
Hypothesis
Vascular alterations occurring in Raynaud phenomenon result in local lower bone quality and QUS values.
Conclusion
Patients with Raynaud phenomenon, especially those with scleroderma, show reduced bone mass and quality as indicated by quantitative ultrasound.
Supporting Evidence
- Nailfold capillaroscopy revealed minor alterations in 36.8% of patients.
- Major alterations were found in 37.5% of patients.
- A higher frequency of low QUS parameters was observed in patients with major capillaroscopy alterations.
Takeaway
This study found that people with Raynaud phenomenon have weaker bones, especially if they have more severe blood vessel changes.
Methodology
The study measured bone ultrasound parameters and performed nailfold capillaroscopy on females with Raynaud phenomenon.
Potential Biases
Potential bias from the clinical evaluation being conducted by a rheumatologist aware of the capillaroscopy results.
Limitations
The study only included females and may not generalize to males.
Participant Demographics
136 females with a mean age of 53.3 years.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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