Measles still has a devastating impact in unvaccinated populations
2007

Measles Impact in Unvaccinated Children

Sample size: 64000 publication Evidence: moderate

Author Information

Author(s): William J. Moss

Primary Institution: Johns Hopkins University Bloomberg School of Public Health

Hypothesis

Children in Nigeria, Niger, and Chad face high mortality rates from measles despite global declines in measles mortality.

Conclusion

Children in Nigeria, Niger, and Chad still experience unacceptably high mortality from measles, a largely preventable disease.

Supporting Evidence

  • Measles case fatality ratios in endemic areas of sub-Saharan Africa range from 5% to 10%.
  • During a famine in Ethiopia, measles accounted for 22% of deaths among children under five.
  • Vaccinated children have less severe disease and lower mortality rates from measles.

Takeaway

Measles can be very dangerous for kids who aren't vaccinated, and many of them are getting very sick and dying.

Methodology

The study conducted retrospective household surveys in neighborhoods affected by measles outbreaks.

Potential Biases

The study may be subject to recall and misclassification biases.

Limitations

Potential recall and misclassification biases may affect the estimates.

Participant Demographics

The population surveyed included over 64,000 individuals from affected areas.

Digital Object Identifier (DOI)

10.1371/journal.pmed.0040024

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication