Recovering Perfluorocarbon Liquid During Neonatal Ventilation
Author Information
Author(s): Dunster Kimble R, Davies Mark W, Fraser John F
Primary Institution: Institute of Health and Biomedical Innovation, Queensland University of Technology
Hypothesis
This study aimed to determine how much PFC liquid could be recovered using a conventional humidified neonatal ventilator with chilled condensers.
Conclusion
Using two series connected condensers in the ventilator expiratory line, 55% of PFC liquid (FC-77) can be recovered during partial liquid ventilation without altering the function of the ventilator circuit.
Supporting Evidence
- The mean volume of FC-77 recovered was 16.4 mL when condensers were used as the expiratory limb.
- The mean volume of FC-77 recovered was 7.6 mL when condensers were connected to the ventilator exhaust outlet.
- The volume of FC-77 recovered was significantly higher when the condenser was used as an expiratory limb.
Takeaway
The study found that using special coolers can help collect a liquid used in breathing support for babies, which is usually lost in the air.
Methodology
A model lung was used to simulate a 3.5 kg infant, and the recovery of perfluorocarbon liquid was measured using chilled condensers in two configurations.
Limitations
The study was conducted in a controlled environment and may not fully replicate clinical conditions.
Participant Demographics
The model lung approximated a 3.5 kg infant.
Statistical Information
P-Value
< 0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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