Prevalence and associations of anisometropia with spherical ametropia, cylindrical power, age, and sex, based on 134,603 refractive surgery candidates

2025

Anisometropia and Its Associations in Refractive Surgery Candidates

Sample size: 134603 publication 10 minutes Evidence: high

Author Information

Author(s): Deuchert Mona, Frings Andreas, Druchkiv Vasyl, Schweighofer Jakob, Muhammad Sajjad, Linke Stephan, Katz Toam

Primary Institution: Department of Ophthalmology, Medical Faculty and University Hospital Duesseldorf, Heinrich Heine University, Duesseldorf, Germany

Hypothesis

To examine the prevalence and associations of anisometropia with spherical ametropia, cylindrical power, age, and sex.

Conclusion

The study found independent associations between anisometropia and spherical power, cylindrical power, age, and sex in myopic and hyperopic individuals.

Supporting Evidence

The median level of anisometropia was 0.38 D.
The prevalence of anisometropia was found to be 17.9%.
An increase in cylindrical power by 7.8 D reduced the chance of observing anisometropia by half.
Age was positively associated with anisometropia in myopes but negatively in hyperopes.
Female sex was positively related to anisometropia in myopes, while male sex was positively related in hyperopes.

Takeaway

This study looked at a lot of people who needed eye surgery and found that differences in how well each eye sees can be linked to age, gender, and how far-sighted or near-sighted someone is.

Methodology

The study analyzed data from 134,603 refractive surgery candidates from 2010 to 2020, using chi-squared tests, nonparametric tests, and logistic regression to assess associations.