Hepatoprotective effects of Polygonum bistorta and active principle on albino rats intoxicated with carbon tetrachloride
2008

Hepatoprotective Effects of Polygonum bistorta on Rats

publication Evidence: moderate

Author Information

Author(s): Mittal Deepak Kumar, Jaswal Amita, Shukla Sangeeta

Primary Institution: Reproductive Biology and Toxicology Laboratory, School of Studies in Zoology, Jiwaji University, Gwalior (M.P.), India.

Hypothesis

The study aims to evaluate the efficacy of Polygonum bistorta and tannic acid in treating liver damage induced by toxicants.

Conclusion

Polygonum bistorta and tannic acid can reduce liver and kidney damage caused by toxic substances.

Supporting Evidence

  • Administration of Polygonum bistorta and tannic acid significantly normalized the elevated serum enzyme levels.
  • Histopathological alterations in liver and kidney were reversed with treatment.
  • The study suggests the potential of these substances as alternative medicine for liver protection.

Takeaway

This study shows that a plant called Polygonum bistorta can help protect the liver from damage caused by harmful substances.

Methodology

The study involved administering Polygonum bistorta and tannic acid to rats that were given toxic substances to assess their protective effects on liver and kidney.

Participant Demographics

Albino rats were used in the study.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

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