Organic Papers
2011

(2E)-3-(1,3-Diphenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one Crystal Structure

publication Evidence: moderate

Author Information

Author(s): Fun Hoong-Kun, Hemamalini Madhukar, Malladi Shridhar, Poojari Pradeep, Isloor Arun M

Primary Institution: Universiti Sains Malaysia

Hypothesis

The study aims to synthesize and analyze the crystal structure of a new pyrazole derivative.

Conclusion

The crystal structure of the compound is stabilized by hydrogen bonds and π–π interactions.

Supporting Evidence

  • The pyrazole ring in the compound is nearly flat, with very small deviations.
  • Adjacent molecules in the crystal are linked by hydrogen bonds, forming dimers.
  • The structure is further stabilized by weak interactions between the rings.

Takeaway

Scientists made a new chemical compound and looked at its structure to see how its parts fit together.

Methodology

The compound was synthesized using a reaction involving methanol, sodium hydroxide, acetophenone, and formyl pyrazole, followed by crystallization.

Digital Object Identifier (DOI)

10.1107/S1600536811023282

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