Fluid removal in critically ill patients during hemodialysis: is there a role for functional hemodynamic monitoring?
2011

Fluid Removal in Critically Ill Patients During Hemodialysis

Sample size: 28 publication Evidence: moderate

Author Information

Author(s): Passos RH, Batista PB

Primary Institution: Hospital São Rafael, Salvador - BA, Brazil

Hypothesis

Can dynamic parameters of fluid responsiveness be used to monitor fluid removal during hemodialysis in critically ill patients?

Conclusion

The study found that changes in pulse pressure variation during hemodialysis reflect the rate of fluid removal and can help avoid hypoperfusion in patients.

Supporting Evidence

  • Median dialysis duration was 4.5 hours with 2,900 ml of fluid removed.
  • There were 102 hypotensive episodes during the study.
  • Pulse pressure variation increased significantly during dialysis treatment.
  • At the end of the procedure, a significant difference in lactate levels was observed.

Takeaway

Doctors can use special measurements to help remove fluid safely from very sick patients during dialysis.

Methodology

Pulse pressure variation and other hemodynamic parameters were monitored every hour during hemodialysis in mechanically ventilated patients.

Participant Demographics

Mechanically ventilated patients with acute kidney injury.

Statistical Information

P-Value

P < 0.2

Statistical Significance

p<0.2

Digital Object Identifier (DOI)

10.1186/cc10178

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