Survey of Mini-Proteins in Bacteria and Archaea
Author Information
Author(s): Wang Fengyu, Xiao Jingfa, Pan Linlin, Yang Ming, Zhang Guoqiang, Jin Shouguang, Yu Jun
Primary Institution: CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China
Hypothesis
What roles do mini-proteins play in bacteria and archaea?
Conclusion
Mini-proteins are common in bacteria and archaea, with significant variations in their numbers across different species.
Supporting Evidence
- 180,879 mini-proteins were extracted from 532 sequenced genomes.
- Mini-proteins account for approximately 10.99% of all genomic proteins.
- 58.79% of mini-proteins are species-specific.
- 70.03% of mini-proteins are classified as hypothetical proteins.
Takeaway
Mini-proteins are tiny proteins found in bacteria and archaea that help them do important jobs, but we don't know what many of them do yet.
Methodology
Analyzed 532 sequenced genomes and extracted mini-proteins of 100 amino acids or less.
Limitations
Many mini-proteins are hypothetical and their functions remain largely unknown.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website