Enhancing access to reports of randomized trials published world-wide – the contribution of EMBASE records to the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library
2008

Improving Access to Randomized Trials through EMBASE

Sample size: 80000 publication Evidence: moderate

Author Information

Author(s): Lefebvre Carol, Eisinga Anne, McDonald Steve, Paul Nina

Primary Institution: UK Cochrane Centre

Hypothesis

Can a search strategy be devised to identify reports of randomized trials in EMBASE that are not indexed in MEDLINE?

Conclusion

The study successfully increased access to reports of trials in EMBASE, particularly in non-English languages.

Supporting Evidence

  • Over 80,000 reports of trials were identified that were not indexed in MEDLINE.
  • The search strategy improved access to trials published in languages other than English.
  • Cumulative sensitivity of the search strategy ranged from 0.1% to 60%.

Takeaway

This study helps people find more reports of medical trials, especially those written in languages other than English, by improving how we search for them.

Methodology

A sensitive search strategy was developed and tested on EMBASE records from 1980 to 2005 to identify trials not indexed in MEDLINE.

Potential Biases

Potential bias due to selective availability of data and reliance on titles and abstracts for identifying trials.

Limitations

The search strategy was based on a small 'gold standard' set and was not validated in an independent test set.

Digital Object Identifier (DOI)

10.1186/1742-7622-5-13

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