When is a GIST not a GIST? A case report of synchronous metastatic gastrointestinal stromal tumor and fibromatosis
2009
Case of a Man with GIST and Fibromatosis
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Lee Chee Khoon, Hadley Alison, Desilva Keshani, Smith Gareth, Goldstein David
Primary Institution: Prince of Wales Hospital, NSW, Australia
Conclusion
Differentiating localized progression of GIST from other diseases has important prognostic and therapeutic implications.
Supporting Evidence
- The patient had long-term stable control of metastatic GIST with systemic therapy.
- Imatinib was initially effective but required dose reduction due to side effects.
- Histopathology revealed a non-malignant fibroid instead of GIST recurrence.
Takeaway
A man with a type of tumor called GIST had surgery, but doctors found another non-cancerous tumor instead. This shows that sometimes, tumors that look similar can actually be different.
Methodology
The case involved surgery and histopathological analysis to differentiate between GIST and other tumors.
Limitations
The case report is based on a single patient, limiting generalizability.
Participant Demographics
A 62-year-old man.
Digital Object Identifier (DOI)
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