Multidrug-Resistant Acinetobacter baumannii Osteomyelitis from Iraq
2008

Multidrug-Resistant Acinetobacter baumannii Osteomyelitis from Iraq

Sample size: 1 publication Evidence: low

Author Information

Author(s): Schafer Jason J., Mangino Julie E.

Primary Institution: Ohio State University Medical Center

Hypothesis

Can tigecycline effectively treat osteomyelitis caused by multidrug-resistant Acinetobacter baumannii?

Conclusion

The treatment with tigecycline was effective in resolving the probable osteomyelitis caused by multidrug-resistant A. baumannii.

Supporting Evidence

  • Tigecycline has shown activity against many multidrug-resistant pathogens, including A. baumannii in vitro.
  • Postoperative recovery included normalization of leukocyte count and decreased wound drainage.
  • The probable osteomyelitis was resolved by standard clinical and radiologic parameters.

Takeaway

A man injured in Iraq got a serious bone infection from a tough germ, but doctors used a special medicine called tigecycline to help him get better.

Methodology

The case involved a patient with a grenade injury who was treated with tigecycline after being diagnosed with osteomyelitis caused by MDR A. baumannii.

Limitations

The role of tigecycline for osteomyelitis with MDR A. baumannii requires further study.

Participant Demographics

A 55-year-old man who was injured in Iraq.

Digital Object Identifier (DOI)

10.3201/eid1403.070128

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