Missed Diagnosis of Cardiac Amyloidosis in a Patient with Normal Wall Thickness
Author Information
Author(s): Li Xiaohui, Mu Tongge, Deng Yangxue, Zhang Yu, Ti Yun, Zhang Lei
Primary Institution: National Key Laboratory for Innovation and Transformation of Luobing Theory, Jinan, China
Hypothesis
Can cardiac amyloidosis be diagnosed in patients with normal left ventricular wall thickness?
Conclusion
Cardiac amyloidosis can be overlooked in patients with normal wall thickness, highlighting the need for increased clinical suspicion.
Supporting Evidence
- Cardiac amyloidosis can present without increased wall thickness.
- Normal wall thickness in echocardiography can lead to missed diagnoses of cardiac amyloidosis.
- Two-dimensional speckle-tracking echocardiography can enhance clinical suspicion of cardiac amyloidosis.
Takeaway
Sometimes, doctors might miss a heart problem called cardiac amyloidosis if the heart looks normal on tests. This case shows that even if the heart walls are normal, there could still be a serious issue.
Methodology
The case involved echocardiography, cardiac magnetic resonance imaging, and biopsy to diagnose cardiac amyloidosis.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A 50-year-old female patient.
Digital Object Identifier (DOI)
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