Fecal microbiota transplantation in severe pneumonia: a case report on overcoming pan-drug resistant Klebsiella pneumoniae infection
2024

Fecal Microbiota Transplantation in Severe Pneumonia

Sample size: 1 publication Evidence: low

Author Information

Author(s): Zhuang Liying, You Yanjing, Zeng Shenyuan, Yu Zongyang, Wang Huijuan, Chen Meiyan, Wen Wen

Primary Institution: Fuzong Clinical Medical College of Fujian Medical University

Hypothesis

Can fecal microbiota transplantation (FMT) effectively treat severe pneumonia caused by pan-drug resistant Klebsiella pneumoniae?

Conclusion

FMT was effective in improving the patient's condition and eradicating the pan-drug resistant Klebsiella pneumoniae infection.

Supporting Evidence

  • Post-FMT, the patient showed significant clinical improvement.
  • FMT enhanced the abundance of beneficial microbiota.
  • The patient was discharged after 133 days of hospitalization.

Takeaway

Doctors used poop from a healthy person to help a very sick lady with pneumonia get better and stop her bad germs from growing.

Methodology

A case report of a 95-year-old female patient treated with FMT after conventional treatments failed.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

95-year-old female patient with severe pneumonia and multiple comorbidities.

Digital Object Identifier (DOI)

10.3389/fmed.2024.1451751

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