New Jersey Center for Tourette Syndrome Sharing Repository: methods and sample description
Author Information
Author(s): Heiman Gary A, King Robert A, Tischfield Jay A
Primary Institution: Rutgers University
Hypothesis
The repository aims to identify genetic factors that play a causal role in Tourette Syndrome and related disorders.
Conclusion
Opening access to the data and patient material to the widest possible research community will hasten the identification of causal genetic factors and facilitate better understanding and treatment of Tourette Syndrome.
Supporting Evidence
- The repository provides clinical data, DNA, and lymphoblastoid cell lines to researchers.
- Subjects were evaluated according to strict DSM-IV-TR criteria for Tourette Syndrome.
- Data collection is ongoing, with a goal of expanding the sample size significantly.
Takeaway
This study created a resource where researchers can access data and samples from people with Tourette Syndrome to help find out what causes it.
Methodology
Subjects were recruited from the Tourette Syndrome Association of New Jersey and evaluated by a child psychiatrist, with DNA samples collected for analysis.
Limitations
The study is ongoing and aims to collect data from approximately 1000 individuals, which may limit the current findings.
Participant Demographics
Of the 75 probands evaluated, 23 were female and 52 were male.
Digital Object Identifier (DOI)
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