6,9-Dimethoxy-3,4-dihydro-1H-1,4-oxazino[4,3-a]indol-1-one
2011
New Compound with Biological Properties
publication
Evidence: moderate
Author Information
Author(s): Salas Cristian O., Tapia Ricardo A., Prieto Yolanda
Primary Institution: Departamento de Química Orgánica, Facultad de Química, Pontificia Universidad Católica de Chile
Hypothesis
The study aimed to find new compounds with biological properties through the synthesis of a specific oxazinoindole.
Conclusion
The synthesized compound has confirmed bond lengths and angles that are within expected values, indicating a stable structure.
Supporting Evidence
- The compound was synthesized with the aim of finding new compounds with biological properties.
- Bond lengths and angles are within the expected values.
- The structure is stabilized by weak hydrogen bonds and π–π stacking interactions.
Takeaway
Scientists made a new chemical compound that might help in medicine, and they checked to make sure it has the right shape.
Methodology
The compound was synthesized by reacting ethyl 1-(2-bromoethyl)-4,7-dimethoxy-1H-indole-2-carboxylate with sodium azide in refluxing dioxane.
Digital Object Identifier (DOI)
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