Effectiveness of Newcastle Disease Vaccines in Broiler Chickens
Author Information
Author(s): Chansiripornchai N, Sasipreeyajan J
Primary Institution: Chulalongkorn University
Hypothesis
Can live Newcastle disease vaccines combined with inactivated oil adjuvant vaccines provide better protection against Newcastle disease in broiler chickens?
Conclusion
The study found that simultaneous vaccination with live B1 or Ulster 2C vaccines and inactivated oil adjuvant vaccines significantly improved disease resistance in broiler chickens.
Supporting Evidence
- All chickens in the unvaccinated control group died after challenge.
- Chickens vaccinated with Ulster 2C showed better disease resistance than those vaccinated with B1.
- The morbidity rate was significantly lower in the Ulster 2C group compared to the B1 group.
- Simultaneous vaccination provided protection without the need for a booster.
- Body weight gain and feed conversion ratio were significantly better in the Ulster 2C group.
Takeaway
This study shows that giving baby chickens two types of vaccines together helps them stay healthy and fight off a serious disease.
Methodology
Broiler chicks were divided into three groups and vaccinated with different combinations of live and inactivated vaccines, then challenged with Newcastle disease virus at 28 days old.
Potential Biases
Potential bias in the selection of vaccine strains and the management of the experimental conditions.
Limitations
The study was limited to a specific breed of broiler chickens and may not be generalizable to other breeds.
Participant Demographics
One-day-old ROSS-308 broiler chicks.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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