Successful Treatment of Candida auris Ventriculitis With Intravenous Liposomal Amphotericin B and Oral Flucytosine: A Case Report
2024

Successful Treatment of Candida auris Ventriculitis

Sample size: 1 publication Evidence: low

Author Information

Author(s): Kang Nayoung, Hsu Victor Yu-Ching, Bailey Charles Christopher Jr

Primary Institution: Providence St Joseph Hospital, Orange, California, USA

Hypothesis

Can intravenous liposomal amphotericin B and oral flucytosine effectively treat Candida auris ventriculitis?

Conclusion

The treatment of Candida auris ventriculitis with liposomal amphotericin B and flucytosine was successful, leading to resolution of the infection.

Supporting Evidence

  • Candida auris is a rapidly emerging fungal pathogen associated with high resistance rates.
  • The patient had a ventriculoperitoneal shunt, which is a risk factor for C auris infection.
  • Antifungal therapy led to resolution of infection without complications.

Takeaway

A man with a serious infection caused by a fungus called Candida auris got better after doctors gave him two special medicines through an IV and by mouth.

Methodology

The patient was treated with intravenous liposomal amphotericin B and oral flucytosine after being diagnosed with Candida auris ventriculitis.

Limitations

This is a single case report, which may limit the generalizability of the findings.

Participant Demographics

A 41-year-old Asian man with multiple comorbidities.

Digital Object Identifier (DOI)

10.1093/ofid/ofae743

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