Evaluating Granulomatous Inflammation in Cytology
Author Information
Author(s): Majeed Muhammad Mudassar Bukhari, Mulazim Hussain
Primary Institution: King Edward Medical University
Hypothesis
This study aims to determine the frequency of cases positive for AFB and fungus in patients diagnosed with granulomatous inflammation on Fine Needle Aspiration Cytology using special stains.
Conclusion
Special stains should be performed on all granulomatous inflammation cases seen on FNAC to confirm TB and rule out other infectious causes.
Supporting Evidence
- 44% of cases were positive for AFB, indicating a significant presence of tuberculosis.
- 5% of cases were positive for fungus, highlighting the need for differential diagnosis.
- Cervical lymph nodes were the most commonly involved site in 87% of cases.
- 93% of AFB positive cases were associated with caseation necrosis.
Takeaway
Doctors can use special stains on samples to find out if a patient has tuberculosis or a fungal infection, which helps them give the right treatment.
Methodology
A descriptive cross-sectional survey was conducted on 100 cases of granulomatous inflammation diagnosed on FNAC, using special stains like ZN, GMS, and PAS.
Limitations
The study does not include comparison with histology and other microbiological detection methods due to cost and unavailability issues.
Participant Demographics
78% of patients were below 30 years of age, with a mean age of 25.14 years; 62% were female and 38% were male.
Digital Object Identifier (DOI)
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