Neoadjuvant Cetuximab Leading to a Complete Pathologic Response in Locally Advanced Lip Squamous Cell Carcinoma
2024

Cetuximab for Lip Squamous Cell Carcinoma Treatment

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Alchaikh Hassan Ruba, Gafarzadeh Zahra, Salmasi Shiva, Hyams David M, Dasanu Constantin A

Primary Institution: Eisenhower Health, Rancho Mirage, USA

Hypothesis

Can neoadjuvant cetuximab lead to a complete pathologic response in locally advanced lip squamous cell carcinoma?

Conclusion

The patient achieved a complete pathologic response to neoadjuvant cetuximab therapy.

Supporting Evidence

  • Cetuximab led to a significant reduction in tumor size.
  • The patient had no signs of recurrence at the 24-week follow-up.
  • This is the first documented case of cetuximab used as neoadjuvant treatment for lip SCC.

Takeaway

A man with lip cancer got better after taking a medicine called cetuximab before surgery, showing that it can help treat this type of cancer.

Methodology

The patient received neoadjuvant cetuximab therapy followed by radical tumor resection.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

An 81-year-old Caucasian male with a history of multiple comorbidities.

Digital Object Identifier (DOI)

10.7759/cureus.75000

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