Treatment of Budd-Chiari Syndrome with Combined Shunts
Author Information
Author(s): Orloff, M.J., Daily, P.O.
Primary Institution: The American Journal of Surgery
Hypothesis
Can combined portal and vena caval decompression effectively treat Budd-Chiari syndrome caused by inferior vena cava occlusion?
Conclusion
Combined portal and vena caval shunt is effective in treating Budd-Chiari syndrome with a low incidence of graft thrombosis.
Supporting Evidence
- 12 control rats survived a sham thoracolaparotomy, 16 rats survived a mesoatrial shunt, and 16 rats survived combined PCS and CAS graft.
- Only 2 of 16 rats that underwent combined PCS and CAS developed graft thrombosis.
- All five patients were alive and well 6 months to 7.5 years postoperatively with patent grafts.
Takeaway
Doctors found a way to help people with a serious liver problem by using special tubes to improve blood flow, which helped many patients feel better.
Methodology
The study involved both animal experiments and clinical evaluations of patients undergoing combined portal and vena caval decompression.
Limitations
No controlled studies comparing different decompression procedures were conducted.
Participant Demographics
Five patients with Budd-Chiari syndrome and ascites were evaluated clinically.
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