Possible Emergence of West Caucasian Bat Virus in Africa
2008

West Caucasian Bat Virus Found in Africa

Sample size: 1221 publication Evidence: moderate

Author Information

Author(s): Kuzmin Ivan V., Niezgoda Michael, Franka Richard, Agwanda Bernard, Markotter Wanda, Beagley Janet C., Urazova Olga Yu, Breiman Robert F., Rupprecht Charles E.

Primary Institution: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Hypothesis

Is West Caucasian bat virus emerging in Africa?

Conclusion

The study found evidence of West Caucasian bat virus in Miniopterus bats in Kenya, suggesting its potential emergence in Africa.

Supporting Evidence

  • Seroprevalence of WCBV in Miniopterus bats ranged from 17% to 26%.
  • Seropositive bats were found in 4 out of 5 locations sampled.
  • Only 1 out of 76 serum samples with WCBV-neutralizing activity also neutralized DUVV.
  • Females had a higher seroprevalence (26%) compared to males (19%).

Takeaway

Researchers found a virus in bats in Africa that was previously only known in Europe, which could mean it is spreading.

Methodology

Bats were collected from various locations in Kenya, and their serum was tested for neutralizing antibodies against West Caucasian bat virus.

Limitations

The study could not isolate the virus, and the seroprevalence may reflect past exposures rather than current infection.

Participant Demographics

Bats of at least 30 species were collected, with a focus on Miniopterus bats.

Statistical Information

P-Value

0.12

Confidence Interval

95% confidence interval 17–27

Statistical Significance

p = 0.12

Digital Object Identifier (DOI)

10.3201/eid1412.080750

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