Comparing Ampicillin/Sulbactam and Cefoxitin for Treating Pelvic Inflammatory Disease
Author Information
Author(s): Joseph G. Jemsek, Frank Harrison
Primary Institution: Charlotte Memorial Hospital
Hypothesis
Is ampicillin plus sulbactam as effective and safe as cefoxitin for treating pelvic inflammatory disease?
Conclusion
Ampicillin/sulbactam is as effective and safe as cefoxitin for treating pelvic inflammatory disease.
Supporting Evidence
- 67% of patients treated with ampicillin/sulbactam experienced clinical cure.
- 68% of patients treated with cefoxitin experienced clinical cure.
- Pathogens were eradicated in 70% of women given ampicillin/sulbactam.
- Pathogens were eradicated in 56% of women given cefoxitin.
Takeaway
This study looked at two medicines to treat a common infection in women. Both worked well, but ampicillin/sulbactam might be easier to use.
Methodology
A randomized, prospective, third-party-blinded, comparative study with 93 women diagnosed with pelvic inflammatory disease.
Limitations
The study was limited to a single site and had a relatively small sample size.
Participant Demographics
Women aged 14 and older with a diagnosis of pelvic inflammatory disease.
Statistical Information
P-Value
P 0.67
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