Minimum Information About a Simulation Experiment (MIASE)
2011

Minimum Information About a Simulation Experiment (MIASE)

publication Evidence: high

Author Information

Author(s): Waltemath Dagmar, Adams Richard, Beard Daniel A., Bergmann Frank T., Bhalla Upinder S., Britten Randall, Chelliah Vijayalakshmi, Cooling Michael T., Cooper Jonathan, Crampin Edmund J., Garny Alan, Hoops Stefan, Hucka Michael, Hunter Peter, Klipp Edda, Laibe Camille, Miller Andrew K., Moraru Ion, Nickerson David, Nielsen Poul, Nikolski Macha, Sahle Sven, Sauro Herbert M., Schmidt Henning, Snoep Jacky L., Tolle Dominic, Wolkenhauer Olaf, Le Novère Nicolas

Hypothesis

What is the minimum information required to enable the reproducibility of simulation experiments in computational biology?

Conclusion

MIASE guidelines improve the quality of scientific reporting and facilitate the reproducibility of simulation experiments.

Supporting Evidence

  • MIASE guidelines define the core information necessary for performing simulations of models.
  • Following MIASE will improve the quality of scientific reporting.
  • MIASE allows for the reproduction of any simulation experiment.
  • Standardization is essential for facilitating the exchange and interpretation of scientific research outcomes.
  • MIASE compliance will enhance the sharing of simulation procedures.

Takeaway

Scientists need to share specific details about their experiments so others can repeat them. MIASE helps make sure everyone knows what information to include.

Methodology

The paper outlines the MIASE guidelines, which specify the minimum information necessary for describing simulation experiments in computational biology.

Limitations

MIASE does not cover the correctness of simulation results or the assumptions made during model design.

Digital Object Identifier (DOI)

10.1371/journal.pcbi.1001122

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