The absolute structure of ptilosarcenone 2.5-hydrate, a diterpenoid briarane from the orange sea pen Ptilosarcus gurneyi
2011
Structure of Ptilosarcenone from Sea Pen
publication
Evidence: high
Author Information
Author(s): Nurco Daniel J., Conklin Douglas E., Shapiro Nathan S., Tran Elaine
Primary Institution: Department of Animal Science, University of California
Hypothesis
The study aims to determine the absolute structure of ptilosarcenone, a diterpenoid briarane.
Conclusion
The absolute configuration of ptilosarcenone was determined unambiguously, showing similar stereochemistry to other briaranes.
Supporting Evidence
- The study provides a detailed crystallographic analysis of ptilosarcenone.
- Two organic molecules and five disordered water molecules were identified in the structure.
- The absolute configuration was determined with a Flack parameter of 0.06.
Takeaway
Scientists figured out the exact shape of a special molecule from a sea creature, which is similar to other molecules they studied before.
Methodology
Crystals of ptilosarcenone were grown from a binary solvent system using ethanol and water.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website