Lateral Flow Immunosensing of Salmonella Typhimurium Cells in Milk: Comparing Three Sequences of Interactions
2024

Detecting Salmonella in Milk Using Lateral Flow Immunoassays

publication Evidence: high

Author Information

Author(s): Byzova Nadezhda A., Safenkova Irina V., Gorbatov Alexey A., Biketov Sergey F., Dzantiev Boris B., Zherdev Anatoly V.

Primary Institution: A.N. Bach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences

Hypothesis

Can different formats of lateral flow immunoassays (LFIA) improve the detection of Salmonella Typhimurium in milk?

Conclusion

The study found that the common sandwich LFIA format was the most effective for detecting Salmonella Typhimurium in milk samples.

Supporting Evidence

  • The detection limits for the LFIA formats were 3 × 10^4, 1 × 10^5, and 3 × 10^5 cells/mL.
  • Format A showed recovery values of 70–110% for Salmonella detection in milk.
  • Format A was the most sensitive and efficient technique for Salmonella detection in milk.

Takeaway

This study tested three ways to check milk for a germ called Salmonella. The easiest way worked best and helped find the germ quickly.

Methodology

The study compared three LFIA formats for detecting Salmonella Typhimurium in milk, measuring detection limits and assay times.

Limitations

Formats B and C were less effective in detecting Salmonella in milk compared to format A.

Digital Object Identifier (DOI)

10.3390/microorganisms12122555

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication